Morphine Sulfate Injection Shortage: Updates on Availability and Manufacturer Status

What’s in Shortage

Morphine Sulfate Injection (Brand Name: MORPHINE SULFATE) is currently listed as in shortage. This medication is categorized under Analgesia/Addiction and is provided in an injection dosage form. The shortage status is currently active.

Which Manufacturers Are Affected

Fresenius Kabi USA, LLC is the manufacturer reported in the current database update. Availability varies significantly by specific presentation:

• Morphine Sulfate, Injection, 5 mg/1 mL (NDC 63323-455-01): Unavailable. Not available at this time.
• Morphine Sulfate, Injection, 4 mg/1 mL (NDC 76045-005-11): Available. Check wholesalers for inventory.
• Morphine Sulfate, Injection, 2 mg/1 mL (NDC 63323-452-01): Unavailable. Next release not available at this time. Check wholesalers for inventory.
• Morphine Sulfate, Injection, 2 mg/1 mL (NDC 76045-004-11): Unavailable. Next release expected February 2026. Check wholesalers for inventory.
• Morphine Sulfate, Injection, 10 mg/1 mL (NDC 63323-451-01): Unavailable. Next release not available at this time.
• Morphine Sulfate, Injection, 4 mg/1 mL (NDC 63323-454-01): Available. Check wholesalers for inventory.

For more information, Fresenius Kabi USA, LLC can be contacted at 888-386-1300.

Why There’s a Shortage

The FDA indicates that the primary reason for this shortage is a demand increase for the drug.

What Patients Should Do

If you are affected by this shortage, please take the following steps:

• Consult your healthcare provider: Discuss your treatment options and any concerns regarding the availability of your medication. Do not make any changes to your treatment plan without medical supervision.
• Talk to your pharmacist: Pharmacists often have the most up-to-date information regarding local stock and can check with various wholesalers.
• Contact the manufacturer: You may use the contact information provided above to inquire about supply timelines.

Disclaimer: This article is for informational purposes only and does not constitute medical advice. Patients should always consult with their healthcare provider for medical guidance.

Source

Attribution: FDA Drug Shortage Database Initial Posting Date: 10/31/2017 Last Updated: 02/05/2026