Amino Acid Injection Shortage: Status Updates for Premasol, Aminosyn-PF, and Other Brands

What’s in Shortage

Amino Acid Injection, a medication within the gastroenterology therapeutic category, is currently experiencing supply disruptions. This shortage affects several brand-name products, including PREMASOL, PLENAMINE, AMINOSYN II, CLINISOL, TROPHAMINE, AMINOSYN-PF, TRAVASOL, and PROSOL. The shortage was first posted on December 8, 2020, and was most recently updated on February 2, 2026.

Which Manufacturers Are Affected

Availability varies significantly by manufacturer and specific product presentation:

• Baxter Healthcare: Most presentations of Premasol, Clinisol, Prosol, and Travasol are currently Available. However, one presentation of Travasol (NDC 0338-0644-06) is under Limited Availability with an estimated recovery date of February 2026.

  • Contact: 888-229-0001

• Otsuka ICU Medical LLC (Distributed by ICU Medical): Aminosyn II (10% and 15%) is currently Available. However, Aminosyn-PF 7% (NDC 0990-4178-03) and Aminosyn-PF 10% (NDC 0990-4179-05) are currently Unavailable with the recovery date to be determined (TBD).

  • Contact: 1-866-829-9025 or ProductAvailability@icumed.com

• B. Braun Medical Inc.: All listed presentations of Plenamine and TrophAmine 10% are currently Available.

  • Contact: 800-227-2862

Why There’s a Shortage

The FDA source data does not provide a specific reason for the current shortage of these amino acid injection products.

What Patients Should Do

Patients who rely on these injections for nutritional support should be aware that while many versions are available, specific formulations (particularly Aminosyn-PF) may be difficult to obtain.

• Consult Your Healthcare Provider: Speak with your doctor or specialist regarding the availability of your specific formulation. They can determine if an available brand or concentration is appropriate for your clinical needs.
• Talk to Your Pharmacist: Pharmacists often have the most up-to-date information on which NDCs (National Drug Codes) are currently in stock or can be ordered.
• Contact Manufacturers: If you are having difficulty locating a specific product, you may use the contact information provided above to inquire about regional availability.

Disclaimer: This information is for educational purposes only. Patients should always consult with their healthcare provider or pharmacist for medical advice and guidance regarding medication changes or alternatives.

Source

Information provided by the FDA Drug Shortage Database.