Midazolam Hydrochloride Injection Shortage: Current Availability and Manufacturer Updates

What’s in Shortage

Midazolam Hydrochloride Injection is currently listed in shortage. This medication, which falls under the therapeutic categories of Anesthesia and Neurology, is available under the brand names MIDAZOLAM, MIDAZOLAM HYDROCHLORIDE, and MIDAZOLAM IN SODIUM CHLORIDE. The shortage affects various presentations of the injection dosage form. This status was first posted on April 2, 2020, and was most recently updated on February 5, 2026.

Which Manufacturers Are Affected

Several manufacturers are involved in the supply of Midazolam Hydrochloride Injection, with varying levels of availability:

• Fresenius Kabi USA, LLC (Contact: 888-386-1300)

  • Available: 1 mg/1 mL (NDC 63323-411-12 and 63323-411-25), 5 mg/1 mL (NDC 63323-412-25 and 63323-412-02), and Preservative Free 2 mg/2 mL (NDC 76045-211-20). The manufacturer advises checking wholesalers for inventory.
  • Unavailable: 1 mg/1 mL (NDC 63323-411-10) and 5 mg/1 mL (NDC 63323-412-10).

• Avet Pharmaceuticals, Inc. (Contact: 855-228-9470)

  • Available: 1 mg/1 mL (NDC 23155-600-41) and 5 mg/1 mL (NDC 23155-601-42).
  • Unavailable: 5 mg/1 mL (NDC 23155-601-41). The estimated recovery date for this presentation is February 11, 2026.

• WG Critical Care (Contact: 888-493-0861)

  • Available: Midazolam in 0.9% Sodium Chloride, 1 mg/1 mL (NDC 44567-611-10 and 44567-610-10). Patients and providers are encouraged to check wholesalers and distributors for inventory.

Why There’s a Shortage

The source data does not provide a specific reason for the current shortage of Midazolam Hydrochloride Injection.

What Patients Should Do

Patients who require Midazolam Hydrochloride Injection should be aware that while some presentations are unavailable, others remain in supply. If you are concerned about how this shortage may affect your care, please take the following steps:

• Consult your healthcare provider: Discuss your treatment plan and any concerns regarding medication availability.
• Speak with your pharmacist: They can provide the most current information on local stock and wholesaler availability.
• Contact manufacturers: You may use the contact information provided above to inquire about specific product availability.

Disclaimer: Patients should always consult with their healthcare provider regarding medical advice, diagnosis, or treatment.

Source

Information provided by the FDA Drug Shortage Database.